Searchable abstracts of presentations at key conferences on calcified tissues

ba0002op7 | (1) | ICCBH2013

Bone mineralization density distribution, bone formation rate and bone turnover markers in a cohort of children with CKD before and after GH treatment

Fratzl-Zelman Nadja , Nawrot-Wawrzyniak Kamilla , Misof Barbara , Panczyk-Tomaszewska Malgorzata , Ziolkowska Helena , Roschger Paul , Klaushofer Klaus

Background and methods: A specific skeletal complication in children with CKD is growth impairment. The effects of recombinant human growth hormone (rhGH) therapy on bone turnover and bone material quality are not well understood. Bone matrix mineralization density distribution (BMDD) as assessed by quantitative backscattered electron microscopy (qBEI) is an important determinant of bone material quality and reflects bone turnover (average tissue age) and mineralization kineti...